Vol. 7, Issue 2, Part B (2025)

Bacopa monnieri, a prominent herb in the Indian Ayurvedic tradition, is renowned for its health benefits, particularly in enhancing cognitive function and supporting the immune system. This remarkable plant is packed with medicinal properties, including memory enhancement, antioxidant effects, promotion of hair growth, and potential anticancer benefits. In this study, we focused on evaluating the antimitotic activity of extracts from organically cultivated Bacopa monnieri using the Allium cepa model. We conducted a thorough phytochemical screening of the extract to identify its phytoconstituents. The hydroalcoholic extract exhibited positive results for several compounds, including alkaloids, flavonoids, sterols, saponins, proteins, and glycosides. To assess the antimitotic potential, we examined the root tips of Allium cepa, targeting the meristematic cells because their growth rate is comparable to that of cancer cells. We calculated the mitotic index and measured mitotic inhibition, comparing our results to both water and the standard antimitotic drug methotrexate. Notably, the hydroalcoholic extract of Bacopa monnieri demonstrated significant effects, highlighting its promising role in antimitotic activity.