Vol. 6, Issue 2, Part A (2024)

The present study was to evaluate the antifertility (oestrous cycle study) potential of Curcuma longa leaves extract (ethanol) on female Wistar rats. The antifertility activity of the ethanol extract of leaf (Curcuma longa) was evaluated by one method namely oestrous cycle study in female rats. In estrous cycle study, the extract (50mg and 100mg/kg b.w) was administered for 15 days to cover three regular estrous cycles. A vaginal smear from each animal was observed every morning and the duration of each stage of the cycle was noted.
The ethanolic extract showed significant increase (p<0.05) in duration of di oestrous phase and significant decrease (p<0.05) in duration of meta oestrous phase as compared to control group. The ethanolic extract of Curcuma longa leaf has Antifertility activity due to presence of phytochemical like flavonoids which justifies the use of this plant for fertility control.