Vol. 5, Issue 1, Part A (2023)

Inflammation is a healthy process resulting from some disturbances or disease. The signs of inflammation are redness, heat, swelling, pain, loss of function. Inflammation process plays a protective role in our body and in some conditions produce some negative effect such conditions include the inflammatory disorders. For overcoming such problems, many natural plant compounds are used to inhibit inflammatory pathways with less side effects. The secondary metabolites like phenolic compounds and flavonoids are responsible for having anti-inflammatory properties. The aim of this study was to evaluate the anti-inflammatory activity of Corn silk (Stigma maydis) and clove (Syzygium aromaticum) in combination by using In vitro evaluation method "Egg albumin denaturation assay". Firstly corn silk and clove are collected and the extraction is performed by maceration and hydro distillation process respectively, followed by phyto chemical screening. Different concentrations (10, 20, 30µg/ml) of plant extracts are prepared and diclofenac was used as standard drug. The percentage inhibition of protein denaturation determine the anti-inflammatory activity. The combined extract of corn silk and clove showed a significant inhibition of protein denaturation than individual extract.