Abstract:
Lawsonia inermis and
Malvastrum coromandelianum important medicinal plants widely used in India as folk medicine. These plants have been used to control diabetes in traditional medicinal systems. In the present study, 50% volume per volume ethanolic extracts of
Lawsonia inermis and
Malvastrum coromandelianum subjected to in vitro analysis of antidiabetic effect by alpha-amylase and alpha-glucosidase inhibitory assay. Inhibitory activity of the hydro-ethanolic extract of the all two plants individually against alpha-amylase enzyme and alpha-glucosidase enzyme were examined in different concentrations (3.90–500 μg/mL), where acarbose used as a positive control. The percentage inhibition of
Lawsonia inermis showed the highest alpha-amylase and alpha‑glucosidase inhibitory activity. Half-maximal inhibitory concentration value
Malvastrum coromandelianum was found for two plants have antidiabetic property, from these two plants
Malvastrum coromandelianum showed potent enzyme inhibition as compared to other plant extracts and standard acarbose.
